With these studies EPIC-CROWN-2 shows completeness for three main reasons: (i) the phase IIa study that will provide all necessary information on pharmacokinetics and safety (ii) the phase IIb study that will provide the safety and efficacy of FBR-002 in the clinical practice. Importantly, EPIC CROWN 2 will be integrated as part of both the large European trial network EU-RESPONSE and the multinational European Adaptive Platform Trial “Solid Act". Most of them having already been working together in European projects. To optimize the indications for the treatment, potency and breath of F(ab’)2 against variants will be assessed in in vitro and in an animal model as well as prospective studies will respectively be done on immune assessment in treated patients and on mitigation of exacerbated immune responses in vivo.įab’entech will coordinate EPIC-CROWN-2 formed by outstanding experts in different project domains that include clinical trials (HISS, Greece), virology (IMAS12, Spain), and immunopathology models and mitigation (BNITM, Germany - IRD, France). In order to save lives and reduce the use and costs of critical care, this therapeutic solution is expected to reduce at least by 50% ICUs admissions and a highly significant mortality rate of treated patients. The main objective of EPIC-CROWN-2 is to rapidly assess, in multicentric clinical trials, an EMA-authorized antiviral immunotherapy based on potent and broad equine neutralizing anti-SARS-CoV-2 polyclonal F(ab’)2 antibodies in COVID-19 patients, including VOC carriers. The event concluded with a clear message, society and, in particular, institutions need to wake up and start to work together to find solutions as water is an increasingly pressing issue that may cause conflict in the future.In the absence of approved specific antiviral therapies for vaccinated-non-responders and the scarce anti-inflammatory therapies, passive immunotherapies with polyclonal immunoglobulins could be considered a part of the solution. Additionally, Benoît reflected on water footprints and the dilemma of water-abundant countries importing goods, typically fruit and vegetables, that are water-intensive to produce, from countries afflected by water distress. This book is then complimented by the collection of statements in 'Blue Ethics: Ethical Perspective on Sustainable, Fair Water Resources and Guidelines'.ĭuring the even, the conversation among the participants focused on two topics: the management of water, and how some countries use contaminated water and the conflict over water control, and how countries through the use of dams control the water flow and access between regions. These booklets were later transformed into the two books launched at the event.īenoît emphasised the importance of understanding the economics of water to be able to understand how and who should manage the water, which is explained in the book 'Water Ethics: Principles and Guidelines'. The outcomes of these encounters were published in a small collection of 10 booklets, accessible only to the local people. These workshops aimed to bring together a range of knowledge on differents issues concerning water and to find solutions. For this reason, he highlighted that has not only shared among its network these two books, but it has endorsed 'Water Ethics: Principles and Guidelines'.ĭuring the event, Benoît explained how this book project started some years ago with the gathering of some experts on a workshop which was repeated annually. He shared the concern has an organisation about the importance of water and its accessibility for the development of societies. Obiora stressed the role of organisations towards influencing action. organised the Book Launch for two of its latest publications: 'Water Ethics: Principles and Guidelines' and 'Blue Ethic: Ethical Perspectives on Sustainable, Fair Water Resources Use and Management'.ĭr Benoît Girardin, presently a lecturer at the Geneva School of Diplomacy and International Relations and co-editor of both publications was invited to present his work and explain the experiences which led him to undertake this project.ĭr Ignace Haaz, Publications Manager, and Dr Obiora Ike, Executive Director, opened the event.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |